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Invitrogen™ CABC1 Polyclonal Antibody

Description
Recommended positive controls: NT2D1, IMR32, mouse heart. Predicted reactivity: Mouse (94%), Rat (93%), Rhesus Monkey (99%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
ADCK3 serine/threonine kinase is a mitochondrial protein similar to yeast ABC1 that is a member of the ADCK family. CABC1 encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found.
Specifications
Specifications
| Antigen | CABC1 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.53 mg/mL |
| Conjugate | Unconjugated |
| Formulation | 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7 |
| Gene | COQ8A |
| Gene Accession No. | Q60936, Q8NI60 |
| Gene Alias | 4632432J16Rik; aarF domain containing kinase 3; aarF domain-containing protein kinase 3; Adck3; AI462003; ARCA2; atypical kinase ADCK3, mitochondrial; Atypical kinase COQ8A, mitochondrial; Cabc1; Chaperone activity of bc1 complex-like; chaperone activity of bc1 complex-like, mitochondrial; chaperone, ABC1 activity of bc1 complex homolog; chaperone, ABC1 activity of bc1 complex like; Chaperone-ABC1-like; Coenzyme Q protein 8A; coenzyme Q8 homolog; coenzyme Q8A; COQ10D4; COQ8; COQ8A; mKIAA0451; PP265; SCAR9 |
| Gene Symbols | COQ8A |
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