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Invitrogen™ beta Galactosidase Polyclonal Antibody

Description
Positive Control: MCF-7 cell lysate, mouse pancreas tissue lysate, rat stomach tissue lysate, PANC-1, rat kidney tissue, human liver tissue, mouse testis tissue. Subcellular Location: Lysosome, perinuclear region.
Beta Galactosidase encodes a member of the glycosyl hydrolase 35 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature lysosomal enzyme. This enzyme catalyzes the hydrolysis of a terminal beta-linked galactose residue from ganglioside substrates and other glycoconjugates. Mutations in this gene have been associated with GM1-gangliosidosis and Morquio B syndrome. Diseases associated with GLB1 include Gm1-Gangliosidosis, Type I and Gm1-Gangliosidosis, Type Ii.
Specifications
Specifications
| Antigen | beta Galactosidase |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4 |
| Gene | GLB1 |
| Gene Accession No. | P16278, P23780 |
| Gene Alias | acid beta-galactosidase; AW125515; betagal; Beta-Gal; Beta-galactosidase; bgal; Bge; Bgl; Bgl-e; Bgl-s; Bgl-t; Bgs; Bgt; C130097A14Rik; EBP; Elastin receptor 1; elastin receptor 1, 67kDa; ELNR1; galactosidase beta 1; galactosidase, beta 1; GLB1; Glb-1; lactase; lysosmal hydrolase; lysosomal beta-galactosidase; lysosomal hydrolase; MPS4B; ßgal; ß-gal; ß-galactosidase |
| Gene Symbols | GLB1 |
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