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Invitrogen™ BAG3 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5120306
Description
Positive test controls include: A-549, HeLa, HepG2, Mouse brain, Mouse testis. Immunogen sequence: PSAVPSSPKS VATEERAAPS TAPAEATPPK PGEAEAPPKH PGVLKVEAIL EKVQGLEQAV DNFEGKKTDK KYLMIEEYLT KELLALDSVD PEGRADVRQA RRDGVRKVQT ILEKLEQKAI DVPGQVQVYE LQPSNLEADQ PLQAIMEMGA VAADKGKKNA GNAEDPHTET QQPEATAAAT SNPSSMTDTP GNPAAP.
BAG3 are among BAG proteins that compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.Chemical Identifiers
| BAG3 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Polyclonal | |
| Liquid | |
| IgG | |
| Human, Mouse, Rat | |
| BAG3 | |
| AA407278; BAG family molecular chaperone regulator 3; BAG3; BAG-3; BCL2 associated athanogene 3; Bcl-2-associated athanogene 3; Bcl2-associated athanogene 3; BCL2-binding athanogene 3; bcl-2-binding protein Bis; Bcl-2-interacting death suppressor; BIS; CAIR-1; DKFZp434E0610; docking protein CAIR-1; MFM6; mg638; MGC104307; MNCb-2243 | |
| BAG3 | |
| Primary | |
| Affinity Chromatography |
| 1.76 mg/mL | |
| ELISA, Immunohistochemistry (Paraffin), Western Blot | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
| O95817, Q9JLV1 | |
| 293524, 29810, 9531 | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 380-575 of human BAG3 (NP_004272.2). | |
| Antibody |
Specifications
| BAG3 | |
| Polyclonal | |
| Unconjugated | |
| BAG3 | |
| AA407278; BAG family molecular chaperone regulator 3; BAG3; BAG-3; BCL2 associated athanogene 3; Bcl-2-associated athanogene 3; Bcl2-associated athanogene 3; BCL2-binding athanogene 3; bcl-2-binding protein Bis; Bcl-2-interacting death suppressor; BIS; CAIR-1; DKFZp434E0610; docking protein CAIR-1; MFM6; mg638; MGC104307; MNCb-2243 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 293524, 29810, 9531 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Immunohistochemistry (Paraffin), Western Blot | |
| 1.76 mg/mL | |
| PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
| O95817, Q9JLV1 | |
| BAG3 | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 380-575 of human BAG3 (NP_004272.2). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |