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Invitrogen™ ASPM Monoclonal Antibody (K52002_11G4), Invitrogen™

Catalog No. MA556234
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50 μL
200 μL
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MA556234 200 μL
MA555854 50 μL
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Catalog No. MA556234 Supplier Invitrogen™ Supplier No. MA556234
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Mouse Monoclonal Antibody

Sequence of this protein is as follows: CKVPLSNENS QVPQSPEDWR KSEVSPRIPE CQGSKSPKAI FEELVEMKSN YYSFIKQNNP KFSAVQDISS HSHNKQPKRR PILSATVTKR KATCTRENQT EINKPKAKRC LNSAVGEHEK VINNQKEKED FHSYLPIIDP ILSKSKSYKN EVTPSSTTAS VARKRKSDGS MEDANVRVAI TEHTEVREIK RIHFSPSEPK TSAVKKTKNV TTPISKRISN REKLNLKKKT DLSIFRTPIS KTNKRTKPII AVAQSSLTFI KPLKTDIPRH PMPFAAKNMF YDERWKEKQE QGFTWWLNFI LTPDDFTVKT

This gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

Antigen ASPM
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone K52002_11G4
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Gene ASPM
Gene Accession No. Q8IZT6
Gene Alias abnormal spindle microtubule assembly; Abnormal spindle protein homolog; Abnormal spindle-like microcephaly-associated protein; ASP; asp (abnormal spindle) homolog, microcephaly associated; Asp homolog; ASPM; Calmbp1; MCPH5
Gene Symbols ASPM
Host Species Mouse
Immunogen Recombinant human ASPM (immunogen range is 411-720).
Purification Method Protein A
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 259266
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b
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