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transforming growth factor, beta receptor II (70/80kDa), Mouse, Polyclonal Antibody, Abnova™
Mouse polyclonal antibody raised against a partial recombinant TGFBR2.
Supplier: Abnova Corporation H00007048A01
Description
This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq
Sequence: IVTDNNGAVKFPQLCKFCDVRFSTCDNQKSCMSNCSITSICEKPQEVCVAVWRKNDENITLETVCHDPKLPYHDFILEDAASPKCIMKEKKKPGETFFMCSCSSSpecifications
| transforming growth factor, beta receptor II (70/80kDa) | |
| Polyclonal | |
| Mouse polyclonal antibody raised against a partial recombinant TGFBR2. | |
| TGFBR2 | |
| AAT3/FAA3/LDS1B/LDS2B/MFS2/RIIC/TAAD2/TGFR-2/TGFbeta-RII | |
| Mouse | |
| 50 μL | |
| Cell Cycle | |
| Primary | |
| Human, Mouse | |
| Serum |
| ELISA, Western Blot | |
| Unconjugated | |
| 50% glycerol | |
| NM_001024847 | |
| TGFBR2 | |
| TGFBR2 (NP_001020018, 62 a.a. ∼ 165 a.a) partial recombinant protein with GST tag. | |
| RUO | |
| Yes | |
| 7048 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |