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  6. 05511AF647M

MilliporeSigma™ anti-TCF-4 Alexa Fluor 647, Clone: 6H5-3,

Catalog No. 05511AF647M
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Quantity:
100 μL
Conjugate:
Alexa Fluor 647
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Catalog No. Quantity Conjugate
05511AF647M 100 μL Alexa Fluor 647
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Catalog No. 05511AF647M Supplier MilliporeSigma™ Supplier No. 05511AF647
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Description

Mouse Monoclonal Antibody

Specifically detects TCF-4 Clone: 6H5-3 in Human, Mouse, Rat samples, and it is validated for Immunocytochemistry

Transcription factor 7-like 2 (UniProt Q9NQB0; also known as HMG box transcription factor 4, hTCF-4, T-cell factor 4, T-cell-specific transcription factor 4, TCF-4) is encoded by the TCF7L2 (also known as TCF4) gene (Gene ID 6934) in human. TCF4, also known as TCF7L2, is expressed widely during development. Gene targeting study indicates that it is required to maintain the crypt stem cells of the small intestine. TCF4 has many different splicing isoforms and they are expressed differentially in tissues and in cancers of different stages. Studies also indicate that variant of the TCF4 gene confers an increased risk of type 2 diabetes.

Specifications

Antigen TCF-4
Applications Immunocytochemistry
Classification Monoclonal
Clone 6H5-3
Conjugate Alexa Fluor 647
Formulation Purified mouse antibody conjugate in PBS with 15mg/ml BSA and 0.1 % sodium azide.
Gene Accession No. Q9NQB0
Gene Symbols TCF7L2, TCF4
Host Species Mouse
Immunogen Amino acids 31-331 of human TCF-4.
Purification Method Protein G purified
Quantity 100 μL
Regulatory Status RUO
Research Discipline Signaling
Primary or Secondary Primary
Gene ID (Entrez) CAB97213.1
Target Species Human, Mouse, Rat
Content And Storage 2°C to 8°C for one year from date of shipment
Form Purified
Isotype IgG2a
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For Research Use Only