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speckle-type POZ protein, Mouse, Purified MaxPab™ Polyclonal Antibody, Abnova™
Mouse polyclonal antibody raised against a full-length human SPOP protein.
Supplier: Abnova Corporation H00008405B01P
Description
This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq
Sequence: MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQSSpecifications
| speckle-type POZ protein | |
| Polyclonal | |
| Mouse polyclonal antibody raised against a full-length human SPOP protein. | |
| SPOP | |
| TEF2 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| 8405 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
| IgG |
| Immunofluorescence, Western Blot | |
| Unconjugated | |
| PBS with no preservative; pH 7.4 | |
| NM_001007226.1 | |
| SPOP | |
| SPOP (NP_001007227.1, 1 a.a. ∼ 374 a.a) full-length human protein. | |
| 50 μg | |
| Primary | |
| Human | |
| Antibody |