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platelet-derived growth factor receptor, alpha polypeptide, Mouse, Clone: 2D2-1A11, Abnova™
Mouse monoclonal antibody raised against a full-length recombinant PDGFRA.
Supplier: Abnova Corporation H00005156M01
Description
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes. [provided by RefSeq
Sequence: LSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQYPMSEEESSDVEIRNEENNSGLFVTVLEVSSASAAHTGLYTCYYNHTQTEENELEGRHIYIYVPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVTLHNSEGVVPASYDSRQGFNGTFTVGPYICEATVKGKKFQTIPFNVYALKGTCIISFLLSpecifications
| platelet-derived growth factor receptor, alpha polypeptide | |
| Monoclonal | |
| Unconjugated | |
| PBS with no preservative; pH 7.4 | |
| BC015186 | |
| PDGFRA | |
| PDGFRA (AAH15186, 25 a.a. ∼ 218 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| 100 μg | |
| Kinases | |
| 5156 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
| IgG1 κ |
| ELISA, In situ PLA, Western Blot | |
| 2D2-1A11 | |
| Mouse monoclonal antibody raised against a full length recombinant PDGFRA. | |
| PDGFRA | |
| CD140A/MGC74795/PDGFR2/Rhe-PDGFRA | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Human | |
| Antibody |