Neurotrophin-3 Polyclonal Antibody, Invitrogen™

Description

Neurotrophin-3 Antibody, PA1-18385, from Invitrogen. Species Reactivity: Chicken, Human, Rat; Applications: ELISA, Immunohistochemistry, Inhibition Assays, Western Blot.

The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.
Host Species: Rabbit
Cross Reactivity: Chicken, Human, Rat
Isotype: IgG
Immunogen: Synthetic peptide corresponding to residues Y(139) A E H K S H R G E Y(149) of human, mouse and rat NT3.
Formulation: 20μg purified antibody (1mg/mL) and no preservative
Synonyms: Neurotrophin-3, Neurotrophic factor, HDNF, Nerve growth factor 2, NGF-2, Ntf3, Ntf-3
Uniprot Accession: P18280, P20783, P25433
Entrez GeneID: 428099, 4908, 81737
Gene Symbol: NTF3
A cross reactivity of less than 0.1% to mouse NGF, recombinant human BDNF and NT4/5 has been shown by dot blot. Reconstitute with 20 ul of distilled water.

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