Neurofilament, Medium chain Polyclonal Antibody, Invitrogen™

Description

Neurofilament, Medium chain Antibody, PA1-10001, from Invitrogen. Species Reactivity: Bovine, Chicken, Equine, Human, Mouse, Porcine, Rat; Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot.

Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. The neurofilament (NF) triplet proteins (∽70, 160, and 200 kDa) occur in both the central and peripheral nervous system and are normally restricted to neurons. The 70 kDa NF-protein can self-assemble into a filamentous structure, whereas the 160 kDa and 200 kDa NF-proteins require the presence of the 70 kDa NF-protein to co-assemble.
Host Species: Chicken
Cross Reactivity: Bovine, Chicken, Equine, Human, Mouse, Porcine, Rat
Isotype: IgY
Immunogen: Partial recombinant protein corresponding to the C-terminus of NF-M
Formulation: 100μL purified antibody in PBS and 10mM sodium azide
Synonyms: NFM, NF-M, NMC,160 kD neurofilament protein, neurofilament medium polypeptide, neurofilament 3, NEF3
Uniprot Accession: O77788, P07197, P08552, P08553, P12839, P16053
Entrez GeneID: 100054178, 18040, 24588, 281347, 396206, 4741
Gene Symbol: NEFM
This product detects Neurofilament, Medium chain in Bovine, Chicken, Equine, Human, Mouse, Porcine and Rat samples. This product has been successfully used in Immunocytochemistry, Immunofluorescence, Immunohistochemistry and Western Blot procedures. The immunogen is Partial recombinant protein corresponding to the C-terminus of NF-M.

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