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Neurofilament, Medium chain Polyclonal Antibody, Invitrogen™


Neurofilament, Medium chain Antibody, PA1-10015, from Invitrogen™. Species Reactivity: Bv, Ck, Eq, Hu, Ms, Po, Rt; Applications: ELISA, ICC, IF, IHC, WB.

Manufacturer: pierce biotechnology inc  PA110015

Catalog No. 01-670-272

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Description & Specifications

Specifications

Applications ELISA
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry
Applications Western Blot
Formulation 100μL unpurified antibody in whole serum and no preservative
Cross Reactivity Bovine
Cross Reactivity Chicken
Cross Reactivity Equine
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Porcine
Cross Reactivity Rat
Gene Accession No. O77788, P07197, P08552, P08553, P12839, P16053
Gene Symbols NEFM
Storage Requirements avoiding freeze/thaw cycles.
Gene ID (Entrez) 100054129, 100625407, 18040, 24588, 281347, 396206, 4741
Species Reactivity Bovine, Chicken, Equine, Human, Mouse, Porcine, Rat
Format Serum
Gene Alias NFM, NF-M, NMC,160 kD neurofilament protein, neurofilament medium polypeptide, neurofilament 3, NEF3
Immunogen Recombinant fusion protein containing the extreme C-terminal segment of rat NF-M
Isotype IgG
Host Species Rabbit
Antigen Neurofilament, Medium chain
Quantity 100μL
Conjugate Unlabeled
Primary or Secondary Primary
Monoclonal or Polyclonal Polyclonal

Neurofilament, Medium chain Antibody, PA1-10015, from Invitrogen. Species Reactivity: Bovine, Chicken, Equine, Human, Mouse, Porcine, Rat; Applications: ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot.

Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. The neurofilament (NF) triplet proteins (∽70, 160, and 200 kDa) occur in both the central and peripheral nervous system and are normally restricted to neurons. The 70 kDa NF-protein can self-assemble into a filamentous structure, whereas the 160 kDa and 200 kDa NF-proteins require the presence of the 70 kDa NF-protein to co-assemble.
Host Species: Rabbit
Cross Reactivity: Bovine, Chicken, Equine, Human, Mouse, Porcine, Rat
Isotype: IgG
Immunogen: Recombinant fusion protein containing the extreme C-terminal segment of rat NF-M
Formulation: 100μL unpurified antibody in whole serum and no preservative
Synonyms: NFM, NF-M, NMC,160 kD neurofilament protein, neurofilament medium polypeptide, neurofilament 3, NEF3
Uniprot Accession: O77788, P07197, P08552, P08553, P12839, P16053
Entrez GeneID: 100054129, 100625407, 18040, 24588, 281347, 396206, 4741
Gene Symbol: NEFM
In Western blot, this antibody detects bands at ∽145kDa in crude homogenates of rat cerebellum homogenate. Human and bovine run slower at ∽160kDa. A minor band at1∽110kDa is also frequently seen, which appears to be an in-vivo proteolytic fragment of NF-M.