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Neurofilament, Heavy chain Polyclonal Antibody, Invitrogen™


Neurofilament, Heavy chain Antibody, PA1-10002, from Invitrogen™. Species Reactivity: Bovine, Human, Mouse, Rat; Applications: ELISA, ICC, IF, IHC, WB.

Manufacturer: pierce biotechnology inc  PA110002

Catalog No. 01-670-259

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Description & Specifications

Specifications

Antigen Neurofilament, Heavy chain
Applications Enzyme Linked Immunosorbent Assay
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry
Applications Western Blot
Conjugate Unlabeled
Cross Reactivity Bovine
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Format Purified
Formulation 50μL purified antibody in PBS and 10mM sodium azide
Gene Accession No. P12036, P16884, P19246
Gene Alias NFH, NHC, NF 200 kD
Gene Symbols NEFH
Host Species Chicken
Immunogen Purified axonal form of bovine NF-H.
Isotype IgY
Quantity 50μL
Species Reactivity Bovine, Human, Mouse, Rat
Storage Requirements avoiding freeze/thaw cycles.
Primary or Secondary Primary
Monoclonal or Polyclonal Polyclonal
Gene ID (Entrez) 24587, 380684, 4744, 528842

Neurofilament, Heavy chain Antibody, PA1-10002, from Invitrogen. Species Reactivity: Bovine, Human, Mouse, Rat; Applications: ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot.

Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. The neurofilament (NF) triplet proteins (∽70, 160, and 200 kDa) occur in both the central and peripheral nervous system and are normally restricted to neurons. The 70 kDa NF-protein can self-assemble into a filamentous structure, whereas the 160 kDa and 200 kDa NF-proteins require the presence of the 70 kDa NF-protein to co-assemble.
Host Species: Chicken
Cross Reactivity: Bovine, Human, Mouse, Rat
Isotype: IgY
Immunogen: Purified axonal form of bovine NF-H.
Formulation: 50μL purified antibody in PBS and 10mM sodium azide
Synonyms: NFH, NHC, NF 200 kD
Uniprot Accession: P12036, P16884, P19246
Entrez GeneID: 24587, 380684, 4744, 528842
Gene Symbol: NEFH
This antibody reacts primarily with the phosphorylated axonal form of NF-H and shows some cross-reactivity with phosphorylated NF-M, which has similar phosphorylation sites to NF-H.