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anti-Neurofilament, Heavy chain Polyclonal, Thermo Scientific™


Neurofilament, Heavy chain Polyclonal Ab PA1-10016 from Thermo Scientific™ detects Neurofilament, Heavy chain in Bv and Rt samples, and is validated for ICC, IF, IHC and WB

Manufacturer: pierce biotechnology inc  PA110016

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Catalog No. 01-670-273

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Description & Specifications

Specifications

Antigen Neurofilament, Heavy chain
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry
Applications Western Blot
Conjugate Unlabeled
Cross Reactivity Bovine
Cross Reactivity Rat
Format Serum
Formulation 100μL unpurified antibody in whole serum and 10mM sodium azide
Gene Accession No. P16884
Gene Alias NFH, NHC, NF 200 kD
Gene Symbols NEFH
Host Species Rabbit
Immunogen Native NF-H purified from bovine spinal cord
Isotype IgG
Quantity 100μL
Species Reactivity Bovine, Rat
Storage Requirements avoiding freeze/thaw cycles.
Primary or Secondary Primary
Monoclonal or Polyclonal Polyclonal
Gene ID (Entrez) 24587, 528842

Neurofilament, Heavy chain Polyclonal Ab PA1-10016 from Thermo Scientific™ detects Neurofilament, Heavy chain in Bv and Rt samples, and is validated for ICC, IF, IHC and WB

Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. The neurofilament (NF) triplet proteins (∽70, 160, and 200 kDa) occur in both the central and peripheral nervous system and are normally restricted to neurons. The 70 kDa NF-protein can self-assemble into a filamentous structure, whereas the 160 kDa and 200 kDa NF-proteins require the presence of the 70 kDa NF-protein to co-assemble.
Host Species: Rabbit
Cross Reactivity: Bovine, Rat
Isotype: IgG
Immunogen: Native NF-H purified from bovine spinal cord
Formulation: 100μL unpurified antibody in whole serum and 10mM sodium azide
Synonyms: NFH, NHC, NF 200 kD
Uniprot Accession: P16884
Entrez GeneID: 24587, 528842
Gene Symbol: NEFH
PA1-10016 detects Neurofilament NF-H, primarily the hyperphosphorylated axonal form which yields a band at ∽200kDa in Western blot applications.