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MAP2 Chicken anti-Human, Mouse, Rat, Polyclonal, Invitrogen™
Chicken Polyclonal Antibody
Manufacturer: Pierce Biotechnology Inc PA110005
DescriptionMAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2a & MAP2b) and a low molecular weight form. The expression of MAP2 is developmentally regulated and its multiple forms arise by alternative splicing of a single gene. MAP2 is involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dendrites, implicating a role in determining and stabilizing dendritic shape during neuron development. MAP2 is useful in studies of neuron structure in normal and maligt brain tissue as well as in degenerative diseases such as Alzheimer′s Disease (AD).
|PBS with 0.02% sodium azide|
|P11137, P20357, P15146|
|Microtubule Associated Protein 2|
|17756, 25595, 4133|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|Recombit human construct of Prot-r-MAP2-P1, Prot-r-MAP2-P2 and Prot-r-MAP2-P3 projection domain sequences (a.a. 377-1505)|
|Human, Mouse, Rat|