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v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, Mouse, Clone: 4F3, Abnova™

Mouse monoclonal antibody raised against a partial recombinant KRAS.

Supplier:  Abnova Corporation H00003845M02

Catalog No. 89-000-769


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Description

Description

This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq

Sequence: KSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTV
Specifications

Specifications

v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Monoclonal
Unconjugated
PBS with no preservative; pH 7.4
NM_004985
KRAS
KRAS (NP_004976, 16 a.a. ∼ 125 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
100 μg
Cell Cycle
Primary
Human
Antibody
ELISA, Western Blot
4F3
Mouse monoclonal antibody raised against a partial recombinant KRAS.
KRAS
C-K-RAS/K-RAS2A/K-RAS2B/K-RAS4A/K-RAS4B/KI-RAS/KRAS1/KRAS2/NS3/RASK2
Mouse
Affinity Purified
RUO
Yes
3845
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
IgG2a κ
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