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KiSS-1 metastasis-suppressor, Mouse, Clone: 1F7, Abnova™
Mouse monoclonal antibody raised against a partial recombinant KISS1.
Supplier: Abnova Corporation H00003814M05
Description
This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may function to inhibit chemotaxis and invasion, attenuating metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. [provided by RefSeq
Sequence: PGEQSLPCTERKPAATARLSRRGTSLSPPPESSGSPQQPGLSAPHSRQIPAPQGAVLVQREKDLPNYNWNSFGLRFGKREAAPGNHGRSAGRGWGAGAGQSpecifications
| KiSS-1 metastasis-suppressor | |
| Monoclonal | |
| Unconjugated | |
| PBS with no preservative; pH 7.4 | |
| NM_002256 | |
| KISS1 | |
| KISS1 (NP_002247, 46 a.a. ∼ 145 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody |
| ELISA, Immunohistochemistry (PFA fixed), Western Blot | |
| 1F7 | |
| Mouse monoclonal antibody raised against a partial recombinant KISS1. | |
| KISS1 | |
| KiSS-1/METASTIN/MGC39258 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| 3814 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
| IgG2a κ |