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kinase insert domain receptor (a type III receptor tyrosine kinase), Mouse, Clone: 4A2, Abnova™
Mouse monoclonal antibody raised against a partial recombinant KDR.
Supplier: Abnova Corporation H00003791M02
Description
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq
Sequence: LPRLSIQKDILTIKANTTLQITCRGQRDLDWLWPNNQSGSEQRVEVTECSDGLFCKTLTIPKVIGNDTGAYKCFYRETDLASVIYVYVQDYRSPFIASVSSpecifications
| kinase insert domain receptor (a type III receptor tyrosine kinase) | |
| Monoclonal | |
| Unconjugated | |
| PBS with no preservative; pH 7.4 | |
| NM_002253 | |
| KDR | |
| KDR (NP_002244, 31 a.a. ∼ 130 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| 100 μg | |
| Angiogenesis | |
| Primary | |
| Human | |
| Antibody |
| ELISA, Western Blot | |
| 4A2 | |
| Mouse monoclonal antibody raised against a partial recombinant KDR. | |
| KDR | |
| CD309/FLK1/VEGFR/VEGFR2 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Yes | |
| 3791 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
| IgG2a κ |