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pancreatic and duodenal homeobox 1, Mouse, Clone: 3F10, Abnova™

Mouse monoclonal antibody raised against a partial recombinant IPF1.

Supplier:  Abnova Corporation H00003651M01

Catalog No. 89-000-757


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Description

Description

The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq

Sequence: LEEPNRVQLPFPWMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKEEDKK
Specifications

Specifications

pancreatic and duodenal homeobox 1
Monoclonal
Unconjugated
PBS with no preservative; pH 7.4
NM_000209
PDX1
IPF1 (NP_000200, 109 a.a. ∼ 208 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
100 μg
Transcription Regulation
Primary
Human
Antibody
ELISA, Western Blot
3F10
Mouse monoclonal antibody raised against a partial recombinant IPF1.
PDX1
GSF/IDX-1/IPF1/IUF1/MODY4/PDX-1/STF-1
Mouse
Affinity Purified
RUO
Yes
3651
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
IgG2b λ
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