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MilliporeSigma™ anti-IL-4 APC, Clone: 11B11,
Rat Monoclonal Antibody
$238.02 - $489.54
Specifications
Antigen | IL-4 |
---|---|
Clone | 11B11 |
Applications | Flow Cytometry |
Classification | Monoclonal |
Conjugate | APC |
Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
MABF1503MI
|
MilliporeSigma™
MABF1503 |
25 μg |
Each for $238.02
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MABF1504MI
|
MilliporeSigma™
MABF1504 |
100 μg |
Each for $489.54
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Description
Specifically detects IL-4 Clone: 11B11 in Mouse samples, and it is validated for Flow Cytometry
The 11B11 antibody binds to mouse Interleukin-4 (IL-4), a 14kDa cytokine that is largely secreted by activated T cells of the Th2 subset, and to some degree by NKT and mast cells. This cytokine acts as a stimulatory factor for B cells, inducing their proliferation and differentiation, as well as playing a role in immunoglobulin class-switching. IL-4 may also provide autocrine stimulation for T cells, and affect the function of antigen presenting cells such as macrophages and dendritic cells. IL-4 can bind and signal via three cell surface receptor types: CD124 by itself, CD124 in combination with the common gamma chain (type I complex), or CD124 combined with CD213a1 (type II complex).The 11B11 antibody is widely used for detection of intracellular levels of IL-4 protein by flow cytometry, as well as for analysis of soluble cytokine as measured by ELISA, and in functional assays to neutralization cytokine-receptor interactions.Specifications
IL-4 | |
Flow Cytometry | |
APC | |
Rat | |
Inflammation, Immunology | |
Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1%Â gelatin, pH 7.2. | |
Il4, Il-4 | |
Primary | |
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze |
11B11 | |
Monoclonal | |
Purified | |
RUO | |
Mouse | |
P07750 | |
Proprietary immunogen | |
Purified by size-exclusion chromatography |
For Research Use Only