LPAR3 Polyclonal Antibody, Invitrogen™

Description

Due to low expression of EDG receptors, it is recommended to use Femto Signal Substrate for Western blot. A suggested positive control for this product is RH7777 cells transfected with EDG7.

EDG7 is a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predomitly to G(q/11) alpha proteins.EDG7 has been reported in human prostate, as well as rodent brain, kidney, lung, placenta, prostate, and testis. ESTs have been isolated from a normal prostate library, as well as cancer libraries of the head/neck, ovary, and thyroid.