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TYROBP Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Supplier: Thermo Fisher Scientific PA112701
Description
A suggested positive control for this product is NKp44 positive cells.
DAP12 is a transmembrane adaptor protein that is non-covalently associated with several cell surface receptors on natural killer (NK), myeloid, and presumably neuronal cells. DAP12 contains an ITAM domain that preferentially recruits the protein tyrosine kinase Syk to initiate signal transduction. Deficiency of DAP12 results in reduced antigen presentation function by myeloid cells and defects in function of certain NK cell receptors in mice, as well as presenile dementia and bone cysts in humans.Specifications
| TYROBP | |
| Polyclonal | |
| Unconjugated | |
| TYROBP | |
| DAP12; DNAX-activation protein 12; KARAP; KAR-associated protein; killer cell activating receptor associated protein; killer cell activating receptor-associated protein; killer-activating receptor-associated protein; Ly83; PLOSL; TYRO protein tyrosine kinase binding protein; TYRO protein tyrosine kinase-binding protein; Tyrobp | |
| Rabbit | |
| Ammonium sulfate precipitation | |
| RUO | |
| 22177, 7305 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Immunoprecipitation, Western Blot | |
| 1 mg/mL | |
| PBS with 0.08% sodium azide | |
| O43914, O54885 | |
| TYROBP | |
| Recombinant DAP12 protein. | |
| 100 μg | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |