CNTF Polyclonal Antibody, Invitrogen™

Description

CNTF Antibody, PA1-18365, from Invitrogen. Species Reactivity: Human, Rat; Applications: ELISA, Immunohistochemistry, Western Blot.

CNTF is a survival promoting factor for different types of neurons in vitro and in vivo. The essential structural features for the biological function of human CNTF were investigated by Thier, M. et al. They showed that deletion of 14 N-terminal and 18 C-terminal amino acids significantly increased bioactivity compared to wild-type CNTF. CNTF is a survival factor for various neuronal cell types, which seems to prevent the degeneration of motor axons after axotomy.
Host Species: Sheep
Cross Reactivity: Human, Rat
Isotype: IgG
Immunogen: Recombinant human CNTF.
Formulation: 100μL unpurified antibody in whole serum and no preservative
Synonyms: Ciliary neurotrophic factor
Uniprot Accession: P20294, P26441
Entrez GeneID: 1270, 25707
Gene Symbol: CNTF
PA1-18365 detects CNTF from human, mouse, and rat samples. PA1-18365 has been successfully used in immunohistochemistry, Western blot, and ELISA procedures. The PA1-18365 immunogen is recombinant human CNTF. Reconstitute with 100 ul of distilled water.

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