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MilliporeSigma™ anti-CD28 Clone: ANC28.1/5D10,
Mouse Monoclonal Antibody
Supplier: MilliporeSigma™ 217669100UG
Description
Specifically detects CD28 Clone: ANC28.1/5D10 in Human samples, and it is validated for Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, T-Cell Activation
Human CD28 is an important co-stimulatory molecule found on all CD4+ T cells and ∽50% of CD8+ T cells. T cell activities attributed to CD28 include prevention of anergy, induction of cytokine gene transcription, stabilization of cytokine mRNA, and activation of CD8+ cytotoxic T lymphocytes. The ligands for CD28, known as CD80 (B7-1) and CD86 (B7-2), are monomeric transmembrane glycoproteins.Specifications
| CD28 | |
| Monoclonal | |
| Unconjugated | |
| Mouse | |
| 100 μg | |
| Primary | |
| Human | |
| Purified |
| Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, T-Cell Activation | |
| ANC28.1/5D10 | |
| In 150mM NaCl, 100mM KCl, 50mM sodium phosphate, pH 7.5. | |
| human CD28 Ig fusion protein and HPB-MLT human tumor cells | |
| RUO | |
| Recognizes CD28 on human T cells and BHK cells transfected with human CD28. | |
| 2°C to 8°C | |
| IgG1 |
For Research Use Only