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MilliporeSigma™ anti-CD11c Red Fluor 710, Clone: N418,
Armenian Hamster Monoclonal Antibody
$238.02 - $401.51
Specifications
Antigen | CD11c |
---|---|
Clone | N418 |
Applications | Flow Cytometry |
Classification | Monoclonal |
Conjugate | Red Fluor 710 |
Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
MABF1501MI
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MilliporeSigma™
MABF1501 |
25 μg |
Each for $238.02
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MABF1502MI
|
MilliporeSigma™
MABF1502 |
100 μg |
Each for $401.51
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Description
Specifically detects CD11c Clone: N418 in Mouse samples, and it is validated for Flow Cytometry
The N418 antibody reacts with mouse CD11c, also known as integrin alpha X. This 150kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha X (CD11c) assembles with Integrin beta-2 (CD18) into a receptor complex known as CR4 which can bind and induce signaling through ICAMs and VCAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.The N418 antibody is widely used as a marker for CD11c expression on dendritic cells (DC), often in parallel with markers for CD11b, for identification of developmental stages and mature subsets of this cell type. CD11c is prominently expressed on tissue macrophages, and is also detected on some types of activated T cells and intestinal intraepithelial lymphocytes (IEL).Specifications
CD11c | |
Flow Cytometry | |
Red Fluor 710 | |
Armenian Hamster | |
Inflammation, Immunology | |
Purified Armenian Hamster monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1%Â gelatin, pH 7.2. | |
Itgax | |
IgG | |
Purified by size-exclusion chromatography |
N418 | |
Monoclonal | |
Purified | |
RUO | |
Mouse | |
Q9QXH4 | |
Proprietary immunogen | |
Primary | |
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze |
For Research Use Only