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cystathionine-beta-synthase, Mouse, Polyclonal Antibody, Abnova™
Mouse polyclonal antibody raised against a full-length recombinant CBS.
Supplier: Abnova Corporation H00000875A01
Description
The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. [provided by RefSeq
Sequence: MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPASESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLSAPLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLLNFVAAQERDQKSpecifications
| cystathionine-beta-synthase | |
| Polyclonal | |
| Mouse polyclonal antibody raised against a full-length recombinant CBS. | |
| CBS | |
| HIP4 | |
| Mouse | |
| 50 μL | |
| Endocrine/Metabolism | |
| Primary | |
| Human | |
| Serum |
| ELISA, Western Blot | |
| Unconjugated | |
| 50% glycerol | |
| BC011381 | |
| CBS | |
| CBS (AAH11381.1, 1 a.a. ∼ 551 a.a) full-length recombinant protein with GST tag. | |
| RUO | |
| Yes | |
| 875 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |