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calcium modulating ligand, Mouse, Polyclonal Antibody, Abnova™
Mouse polyclonal antibody raised against a partial recombinant CAMLG.
Supplier: Abnova Corporation H00000819A01
Description
The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq
Sequence: MESMAVATDGGERPGVPAGSGLSASQRRAELRRRKLLMNSEQRINRIMGFHRPGSGAEEESQTKSKQQDSDKLNSLSVPSVSKRVVLGDSVSTGTTDQQGSpecifications
| calcium modulating ligand | |
| Polyclonal | |
| Mouse polyclonal antibody raised against a partial recombinant CAMLG. | |
| CAMLG | |
| CAML/MGC163197 | |
| Mouse | |
| 50 μL | |
| Yes | |
| 819 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| ELISA, Western Blot | |
| Unconjugated | |
| 50% glycerol | |
| NM_001745 | |
| CAMLG | |
| CAMLG (NP_001736, 1 a.a. ∼ 100 a.a) partial recombinant protein with GST tag. | |
| RUO | |
| Primary | |
| Human | |
| Serum |