CRP Sheep anti-Human, Polyclonal, Invitrogen™

Description

C Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is a pentraxin (cyclic pentameric protein) compound of five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa), that are bound noncovalently to form the physiologic CRP molecule (m.w. 117.5 kDa). C Reactive Protein mediates activities associated with preimmune nonspecific host resistance. It is opsonic, an initiator of the classical complement cascade and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis.

PA1-18304 detects C-reactive protein from human samples.PA1-18304 has been successfully used in Western blot procedures.The PA1-18304 immunogen is recombinant human C-Reactive protein.Reconstitute with 100 ul of distilled water.