c-Fos Polyclonal Antibody, Invitrogen™

Description

c-Fos Antibody, PA1-18330, from Invitrogen. Species Reactivity: Hamster, Rabbit, Rat; Applications: Immunohistochemistry, Western Blot.

c-FOS is a nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. It has a critical function in regulating the development of cells destined to form and maintain the skeleton, and is thought to have an important role in signal transduction, cell proliferation and differentiation.
Host Species: Sheep
Cross Reactivity: Hamster, Rabbit, Rat
Isotype: IgG
Immunogen: Synthetic peptide M(2) F S G F N A D Y E A S S S R C(17) conjugated to diptheria toxoid.
Formulation: 50μg purified antibody (1mg/mL) and no preservative
Synonyms: Cellular Oncogene Fos
Uniprot Accession: P12841
Entrez GeneID: 100348962, 314322
Gene Symbol: FOS, LOC100348962
The immunogenic sequence is homologous in human, rat, mouse, hamster and cat. This antibody has also been shown to cross-react with rabbit cFOS. Reconstitute with 50ul of distilled water. After reconstitution, store aliquots at -20ºC for a higher stability, and at 4ºC with an appropriate antibacterial agent.

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