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BDNF Polyclonal Antibody, Invitrogen™


BDNF Antibody, PA1-18371, from Invitrogen™. Species Reactivity: Human, Rat; Applications: ELISA, Immunohistochemistry, Western Blot.

Manufacturer: pierce biotechnology inc  PA118371

Catalog No. 01-670-623

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Description & Specifications

Specifications

Applications ELISA
Applications Immunohistochemistry
Applications Western Blot
Formulation 100μL unpurified antibody in whole serum and no preservative
Gene ID (Entrez) 24225, 627
Gene Accession No. P23363, P23560
Species Reactivity Human, Rat
Isotype IgG
Gene Symbols BDNF
Storage Requirements Avoid Freeze/Thaw Cycles
Format Serum
Gene Alias Brain-derived neurotrophic factor, Abrineurin
Quantity 100μL
Immunogen Synthetic peptide corresponding to residues H(131) S D P A R R G E L(140) of mouse BDNF.
Cross Reactivity Human
Cross Reactivity Rat
Conjugate Unlabeled
Primary or Secondary Primary
Monoclonal or Polyclonal Polyclonal
Antigen BDNF
Host Species Rabbit

BDNF Antibody, PA1-18371, from Invitrogen. Species Reactivity: Human, Rat; Applications: ELISA, Immunohistochemistry, Western Blot.

BDNF belongs to the neurotrophin family and regulates the survival and differentiation of neurons during development. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer's, and Parkinson's disease. BDNF promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. It is a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
Host Species: Rabbit
Cross Reactivity: Human, Rat
Isotype: IgG
Immunogen: Synthetic peptide corresponding to residues H(131) S D P A R R G E L(140) of mouse BDNF.
Formulation: 100μL unpurified antibody in whole serum and no preservative
Synonyms: Brain-derived neurotrophic factor, Abrineurin
Uniprot Accession: P23363, P23560
Entrez GeneID: 24225, 627
Gene Symbol: BDNF
PA1-18371 detects BDNF from human and rat samples. PA1-18371 has been successfully used in immunohistochemistry, ELISA, and Western blot procedures. The PA1-18371 immunogen is a synthetic peptide corresponding to residues H(131) S D P A R R G E L(140) of mouse BDNF, conjugated to KLH. After reconstitution keep aliquots at -20ºC for a higher stability, and at 4ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles. Reconstitute with 100 ul of distilled water.