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ALS2, Mouse, Clone: 4F10, Abnova™
Mouse monoclonal antibody raised against a partial recombinant ALS2.
Supplier: Abnova Corporation H00057679M02
Description
The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Sequence: PSQDLKPVPERCNQCSQLLITMTDKEDHVIISDSHCCPLGVTLTESQAENHASTALSPSTETLDRQEEVFENTLVANDQSVATELNAVSAQITSSDAMSSSpecifications
| ALS2 | |
| Monoclonal | |
| Unconjugated | |
| PBS with no preservative; pH 7.4 | |
| BC029174 | |
| ALS2 | |
| ALS2 (AAH29174, 221 a.a. ∼ 320 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 κ |
| ELISA, Immunofluorescence, Western Blot | |
| 4F10 | |
| Mouse monoclonal antibody raised against a partial recombinant ALS2. | |
| ALS2 | |
| ALS2CR6/ALSJ/FLJ31851/IAHSP/KIAA1563/MGC87187/PLSJ | |
| Mouse | |
| Affinity chromatography | |
| RUO | |
| 57679 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
| Liquid |