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alpha B Crystallin Polyclonal Antibody, Invitrogen™


alpha B Crystallin Antibody, PA1-16950, from Invitrogen™. Species Reactivity: Human, Mouse; Applications: Immunocytochemistry, Immunofluorescence, Western Blot.

Manufacturer: pierce biotechnology inc  PA116950

Catalog No. 01-950-179

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Description & Specifications

Specifications

Antigen alpha B Crystallin
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Western Blot
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Format Purified
Formulation 100μL purified antibody (1.08mg/mL) in tris citrate and 0.1% sodium azide; pH 7-8
Gene Accession No. P02511, P23927
Gene Alias Alpha crystallin B chain antibody, CryAB antibody, Alpha (B)-crystallin antibody, Rosenthal fiber componet antibody, Heat-shock protein beta-5 antibod
Gene Symbols CRYAB
Host Species Rabbit
Immunogen Synthetic peptide between amino acids 70-140 of the human Crystallin AB protein.
Isotype IgG
Quantity 100μL
Species Reactivity Human, Mouse
Storage Requirements Store at 4° C
Primary or Secondary Primary
Monoclonal or Polyclonal Polyclonal
Gene ID (Entrez) 12955, 1410

alpha B Crystallin Antibody, PA1-16950, from Invitrogen. Species Reactivity: Human, Mouse; Applications: Immunocytochemistry, Immunofluorescence, Western Blot.

Crystallin AB (CryAB) is a developmentally regulated small heat shock protein known to protect cells from stress damage. It may also play an important role in the Golgi reorganization during cell division. CryAB is known to be associated with a number of neurodegenerative pathologies such as Alzheimer disease amd multiple sclerosis. As well, it has been found to be expressed in breast tumors of patients with shorter survival, suggesting that it may be a useful marker in identifying aggressive breast cancer.
Host Species: Rabbit
Cross Reactivity: Human, Mouse
Isotype: IgG
Immunogen: Synthetic peptide between amino acids 70-140 of the human Crystallin AB protein.
Formulation: 100μL purified antibody (1.08mg/mL) in tris citrate and 0.1% sodium azide; pH 7-8
Synonyms: Alpha crystallin B chain antibody, CryAB antibody, Alpha (B)-crystallin antibody, Rosenthal fiber componet antibody, Heat-shock protein beta-5 antibod
Uniprot Accession: P02511, P23927
Entrez GeneID: 12955, 1410
Gene Symbol: CRYAB
This Crystallin AB antibody is useful for Western blot analysis, where a band is seen at ∽20 kDa. There is also a band of greater intensity at ∽40 kDa that may be an aggregated heteromeric complex. CryAB aggregates with homologous proteins, including CryAA and the small heat shock protein HSP28, to form large heteromeric complexes.Suggested positive control: human and mouse skeletal muscle lysate, human skeletal muscle protein, antigen standard for HSPB1 (transient overexpression lysate), mouse skeletal muscle protein.