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Invitrogen™ Angiogenin Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5139827
Description
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: QDNSRYTHFL TQHYDAKPQG RDDRYCESIM RRRGLTSPCK DINTFIHGNK RSIKAICENK NGN Highest antigen sequence indentity to the following orthologs: Rat - 73%, Mouse - 73%.
Angiogenin (ANG or ANG I) is important for the process of neovascularization and formation of new blood vessels. ANG is similar to pancreatic ribonuclease A and functions as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. It interacts with endothelial cell-surface actin and may cause changes in the cell cytoskeleton. ANG is thought to be involved in the development of solid tumors and its antagonists are capable of inhibiting tumor growth. Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9). Angiogenin is a genetic link between ALS and PD.Specifications
| Angiogenin | |
| Polyclonal | |
| Unconjugated | |
| ANG | |
| AI385586; ALS9; ANG; Ang1; Angiogenin; angiogenin ribonuclease 1; angiogenin, ribonuclease A family, member 1; angiogenin, ribonuclease, RNase A family, 5; angiogenin-1; epididymis luminal protein 168; HEL168; MGC22466; MGC71966; RAA1; Ribonuclease 5; ribonuclease A A1; ribonuclease A family member 5; RNase 5; RNASE4; RNASE5; Rnase5a | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 283 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry | |
| 0.05 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| P03950 | |
| ANG | |
| Recombinant protein corresponding to Human ANG. Recombinant protein control fragment (Product #RP-108924). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |