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Invitrogen™ AMPK gamma-1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5104369
Description
Antibody detects endogenous levels of total PRKAG1.
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.Specifications
| AMPK gamma-1 | |
| Polyclonal | |
| Unconjugated | |
| PRKAG1 | |
| 5'-AMP-activated protein kinase subunit gamma-1; 5'-AMP-activated protein kinase, gamma-1 subunit; AA571379; AMP-activated protein kinase, noncatalytic gamma-1 subunit; ampk gamma; AMPK gamma1; AMPK gamma-1 chain; AMPK subunit gamma-1; AMPKG; BB036179; Prkaac; PRKAG1; Prkga1; Protein kinase AMP-activated gamma; protein kinase AMP-activated non-catalytic subunit gamma 1; protein kinase, AMP-activated, gamma 1 non-catalytic subunit | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 19082, 25520, 5571 | |
| -20°C | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| O54950, P54619, P80385 | |
| PRKAG1 | |
| A synthesized peptide derived from human PRKAG1, corresponding to a region within C-terminal amino acids. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |