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Invitrogen™ PureLink™ RNA Mini Kit DFS Item

Provides a simple, reliable, and rapid column-based method for isolating high-quality total RNA from a wide variety of sources without the need for hazardous reagents such as phenol

Manufacturer:  Invitrogen™ 12183025

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Catalog No. 12183025



Rapid and convenient column purification
The PureLink™ RNA Mini Kit provides rapid purification of total RNA from a wide range of cells and tissue types to yield up to 1000μg of purified RNA from a single extraction. High-quality total RNA can be obtained from mini- to midi-prep amounts of starting material with no genomic DNA contamination.

Simplified, nontoxic RNA purification
The PureLink™ RNA Mini Kit combines nontoxic guanidine-isothiocyanate lysis with the speed, purity, and ease-of-use of silica-membrane purification. The safe and easy procedure can typically be completed in less than 20 minutes without the need for hazardous phenol/chloroform extraction, CsCl centrifugation, LiCl, or alcohol precipitation.

  • Obtain high-yield, high-integrity RNA
  • Rapid, non-hazardous RNA purification capabilities
  • Ready-to-use RNA for many downstream applications



Spin Column
20 min.
Any Tissue Type, Bacterial Culture, Blood, Cell Cultures, Liquid Samples (e.g. Serum), Plant, Tissue Homogenates, Tissue Sections, Yeast
Not High-throughput Compatible (Manual)
250 Preps
250 Preps
Room Temperature
Total RNA
350 µg
Silica Spin Column
30 to 100 μL
Total RNA
Microarray Analysis, Next-Generation Sequencing, Real-Time Quantitative PCR (qPCR), Reverse Transcriptase PCR (RT-PCR), Nuclease Protection Assays, Northern Blotting
5x10^6 to 1x10^8 cells, Up to 200 mg of tissue
Product Certifications


For Research Use Only. Not for use in diagnostic procedures.