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AM 580

Catalog No. aaj65155ma
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AAJ65155MA 10 mg
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Catalog No. AAJ65155MA Supplier Thermo Scientific Chemicals Supplier No. J65155MA
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Description

CAS: 102121-60-8 | C22H25NO3 | 351.45 g/mol

Retinoid derivative used for gene expression studies of leukemia-retinoic acid receptor (PHL-RAR) cell line differentiation. AM 580 inhibits tumor proliferation by reducing the level of RARγ and activates RAR β. This receptor increases the expression of disintegrin and metalloprotease.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Retinoid derivative used for gene expression studies of leukemia-retinoic acid receptor (PHL-RAR) cell line differentiation. AM 580 inhibits tumor proliferation by reducing the level of RARγ and activates RAR β. This recep

Chemical Identifiers

CAS 102121-60-8
Molecular Formula C22H25NO3
Molecular Weight (g/mol) 351.45
MDL Number MFCD00673916
InChI Key SZWKGOZKRMMLAJ-UHFFFAOYSA-N
Synonym unii-vz5s5g9zfz, 4-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl carbonyl amino benzoic acid, vz5s5g9zfz, chembl69367, 4-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carboxamido benzoic acid, benzoic acid,4-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl carbonyl amino, 4-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl carbonyl aminobenzoic acid, 4-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl carboxamido benzoic acid, 4-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl carbonyl amino benzoic acid, benzoic acid, 4-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl carbonyl amino
PubChem CID 2126
ChEBI CHEBI:64210
IUPAC Name 4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalene-2-carbonyl)amino]benzoic acid
SMILES CC1(C)CCC(C)(C)C2=CC(=CC=C12)C(=O)NC1=CC=C(C=C1)C(O)=O

Specifications

Color White
Quantity 10 mg
Solubility Information Soluble in DMSO (20mg/ml) or ethanol (10mg/ml).
Formula Weight 351.44
Physical Form Crystalline Solid
Chemical Name or Material AM 580

Safety and Handling

RTECSNumber DH6834890
TSCA No
Recommended Storage Ambient temperatures

RUO – Research Use Only