The QuantiGene Plex Human ADMETOX Panel, 80-plex, enables the measurement of gene expression of all relevant ADME (absorption, distribution, metabolism, and excretion) and toxicological biomarkers through the analysis of 80 RNA targets in a single well using Luminex xMAP technology in combination with branched DNA signal amplification.
The QuantiGene Plex Human ADMETOX Panel, 80-plex, enables the measurement of gene expression of all relevant ADME (absorption, distribution, metabolism, and excretion) and toxicological biomarkers through the analysis of 80 RNA targets in a single well using Luminex xMAP technology in combination with branched DNA signal amplification. Analyze 80 genetic targets implicated in drug metabolism, including enzymes, transporters, and CYPs, as well as toxicology and apoptosis for efficient profiling of your drug discovery and basic research samples.
QuantiGene Plex panels are extensively tested for target combinability, interference, and cross-reactivity to provide the highest level of validation and precision. This kit is not compatible with the MAGPIX instrument.
This panel is used in combination with the QuantiGene Plex Assay Kit (Cat. No. QP1013), which contains all buffers, plates, and detection reagents necessary to perform the assay in 96-well plates. For detailed information, see create custom research panels
Rapid turnaround for this catalog panel for fast delivery
QuantiGene Plex assays are hybridization-based assays for the direct quantitation of RNA from cell lysates, tissue homogenates, or purified RNA. They enable the measurement of multiple targets in the same well via multiplexing.
","teaserText":"The QuantiGene Plex Human ADMETOX Panel, 80-plex, enables the measurement of gene expression of all relevant ADME (absorption, distribution, metabolism, and excretion) and toxicological biomarkers through the analysis of 80 RNA targets in a single well using Luminex xMAP technology in combination with branched DNA signal amplification.","productFeatures":"
QuantiGene Plex panels are extensively tested for target combinability, interference, and cross-reactivity to provide the highest level of validation and precision. This kit is not compatible with the MAGPIX instrument.
This panel is used in combination with the QuantiGene Plex Assay Kit (Cat. No. QP1013), which contains all buffers, plates, and detection reagents necessary to perform the assay in 96-well plates. For detailed information, see create custom research panels
Rapid turnaround for this catalog panel for fast delivery
QuantiGene Plex assays are hybridization-based assays for the direct quantitation of RNA from cell lysates, tissue homogenates, or purified RNA. They enable the measurement of multiple targets in the same well via multiplexing.
QuantiGene Plex panels contain two components: a target-specific probe set and magnetic capture beads. The target-specific probes are used to capture the RNA of interest, and branched DNA technology then amplifies the fluorescent signals, which are read with a Luminex xMAP instrument. The fluorescent signal is directly proportional to the amount of target mRNA present in the sample. This allows for (relative) quantification of gene expression and with this specific panel enables human immune profiling. Detailed and step-by-step data analysis is facilitated by the QuantiGene Plex Gene Expression Assay Ordering.
Features of the QuantiGene Plex Human ADMETOX Panel, 80-plex, include:
True multiplexing—measure 80 genes of interest and housekeeping genes in the same well with no cross-reactivity
Accommodation of difficult sample types—works with degraded and cross-linked RNA in FFPE tissues and blood
Standardized platform—uses 96-well plate format compatible with Luminex 200, FLEXMAP 3D, and INTELLIFLEX systems (384-well format available on demand)
Simple workflow—employs an ELISA-like workflow with direct hybridization of transcripts to beads and transcript labeling (branched DNA signal amplification and PE readout)
Customize with validated targets—if alternative targets are needed in this panel, select from our large inventory of over 22,000 genes to QuantiGene Plex data analysis app.
Applications
QuantiGene Plex assay research applications include compound screening of drug candidates, biomarker verification, siRNA knockdown efficiency, prospective and/or retrospective analysis of clinical samples, microarray validation, predictive toxicology, and detection of translocations and fusion genes. In general, any multiplex gene expression analysis can be done with QuantiGene Plex assays, independent of species or sample type.
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Store probe set and capture beads at 4°C.
Do not freeze the capture beads, as they can be damaged if frozen.
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The QuantiGene Plex Human ADMETOX Panel, 80-plex, enables the measurement of gene expression of all relevant ADME (absorption, distribution, metabolism, and excretion) and toxicological biomarkers through the analysis of 80 RNA targets in a single well using Luminex xMAP technology in combination with branched DNA signal amplification. Analyze 80 genetic targets implicated in drug metabolism, including enzymes, transporters, and CYPs, as well as toxicology and apoptosis for efficient profiling of your drug discovery and basic research samples.
","teaserText":"The QuantiGene Plex Human ADMETOX Panel, 80-plex, enables the measurement of gene expression of all relevant ADME (absorption, distribution, metabolism, and excretion) and toxicological biomarkers through the analysis of 80 RNA targets in a single well using Luminex xMAP technology in combination with branched DNA signal amplification.","productFeatures":"
QuantiGene Plex panels are extensively tested for target combinability, interference, and cross-reactivity to provide the highest level of validation and precision. This kit is not compatible with the MAGPIX instrument.
This panel is used in combination with the QuantiGene Plex Assay Kit (Cat. No. QP1013), which contains all buffers, plates, and detection reagents necessary to perform the assay in 96-well plates. For detailed information, see create custom research panels
Rapid turnaround for this catalog panel for fast delivery
QuantiGene Plex assays are hybridization-based assays for the direct quantitation of RNA from cell lysates, tissue homogenates, or purified RNA. They enable the measurement of multiple targets in the same well via multiplexing.
QuantiGene Plex panels contain two components: a target-specific probe set and magnetic capture beads. The target-specific probes are used to capture the RNA of interest, and branched DNA technology then amplifies the fluorescent signals, which are read with a Luminex xMAP instrument. The fluorescent signal is directly proportional to the amount of target mRNA present in the sample. This allows for (relative) quantification of gene expression and with this specific panel enables human immune profiling. Detailed and step-by-step data analysis is facilitated by the Please try again later.","documentation":"Documentation","ChangeNotification":"Change Notification","viewMoreVersions":"View more versions of this product","version":"Version","selectDownloadOptions":"Select Download Options","certificates":"Certificates","showMore":"Show More","noresultsFound":"No results for lot number","items":"Items","getItNowLearnMore":"Learn More","certificateType":"Certificate Type","sds":"SDS","needItNow":"Need it Now?","safetyServicesDesc":"Take advantage of a range of Safety Services from our trusted suppliers to help ensure the safety and compliance of your people, processes, products, and facilities. Services include assessments, training, equipment maintenance, safety programs, and more.","accessoriesAndServices":"Accessories and Services","highlightDifferences":"Highlight Differences","youMaybeInterested":"you may also be interested in considering","search":"Search","shareContentCorrection":"Share a Content Correction","partialOrderMessage":"The requested quantity exceeds the current inventory in the stockroom below. The exceeded quantity will be backordered.","checkStockroomsDesc":"You are limited to inventory associated to this business account. Change your business account in your account profile or in the cart to view other accounts inventory.","CertificateofValidation":"Certificate of Validation","CertificatesofAnalysis":"Certificate of Analysis","LetterofCertification":"Letter of Certification","email":"Email","seeAlternateProducts":"See alternate available products","technicalDocuments":"Technical Documents","rtecsNumber":"RTECSNumber","accessories":"Accessories","lotNumber":"Lot Number","servicePlan":"Service Plan","productCode":"Catalog Number","CertificateofGuarantee":"Certificate of Guarantee","totalOf":"Total of","brandsLinkText":"Shop All
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![QuantiGene Plex Gene Expression Assay Ordering](https://apps.thermofisher.com/apps/quantigene/#!/importData>QuantiGene Plex data analysis app</a>.</p><p><b>Applications</b></p><p>QuantiGene Plex assay research applications include compound screening of drug candidates, biomarker verification, siRNA knockdown efficiency, prospective and/or retrospective analysis of clinical samples, microarray validation, predictive toxicology, and detection of translocations and fusion genes. In general, any multiplex gene expression analysis can be done with QuantiGene Plex assays, independent of species or sample type.</p>"},"rules":{"viewable":true,"buyable":false,"showPrice":false,"preferred":false,"message":"Please call Customer Service at 1-800-234-7437 or send an email to <a style=\"color:#194166;text-decoration: underline;\" href=\"mailto:help@thermofisher.com\">help@thermofisher.com</a> for assistance.","noStockOrderDisallow":false,"hasCrossRef":false,"addToList":false},"specifications":{"Format":"96-well","For Use With (Application)":"QuantiGene Gene Expression Assay","For Use With (Equipment)":"Luminex Instrument","Content And Storage":"<p>Target-specific probe set and magnetic capture beads (premixed and ready to use).</p><p>Store probe set and capture beads at 4°C.</p><p><b>Do not freeze the capture beads, as they can be damaged if frozen.</b></p>","Product Line":"QuantiGene™ Plex","Product Type":"Multiplex Panel","Quantity":"1 Plate","Shipping Condition":"Wet Ice","Sample Type":"Purified RNA, cell/blood/FFPE lysates, tissue homogenates","Detection Method":"Fluorescence","Research Area":"Toxicology","Species":"Human"},"skuSequence":1,"discontinued":false,"returnable":false,"productTypeCode":"21","skuType":"NONCHEMICAL","authored":true,"vendorPartNumber":"QGP-180-ADMETOX","manufacturerName":"Invitrogen™","skuDifferentiatorText":"80-plex, 1 Plate","erpDescription":"QGP HU ADMETOX PANEL 80PLEX 1","disclaimer":"For Research Use Only. Not for use in diagnostic procedures.","hybrisMetaDescription":"ADMETOX 80-Plex Human QuantiGene Panel enables the study of ADME-implied biomarkers by analyzing 80 RNA targets in a single well using xMAP technology","metaData":{"canonicalUrl":"/shop/products/admetox-80-plex-human-quantigene-plex-panel-3/502417811","keywords":"Invitrogen QuantiGene Plex Human ADMETOX Panel, 80-plex 1 Plate | Buy Online | Invitrogen™ | Fisher Scientific","description":"Invitrogen QuantiGene Plex Human ADMETOX Panel, 80-plex from Invitrogen™. ADMETOX 80-Plex Human QuantiGene Panel enables the study of ADME-implied biomarkers by analyzing 80 RNA targets in a single well using xMAP technology Shop Invitrogen™ QuantiGene™. Available in 1 Plate","title":"Invitrogen QuantiGene Plex Human ADMETOX Panel, 80-plex 1 Plate | Buy Online | Invitrogen™ | Fisher Scientific"},"hasPromo":false,"viewAvailablePromotions":false,"productCompareEnabled":false,"faqEnabled":false,"tpp":false},{"partNumber":"502417809","familyId":"200004748","productTitle":"Invitrogen™ QuantiGene™ Plex Human ADMETOX Panel, 80-plex","productTitleNoGlyphs":"Invitrogen™ QuantiGene™ Plex Human ADMETOX Panel, 80-plex","seoKeyword":"admetox-80-plex-human-quantigene-plex-panel-3","imageGallery":[{"thumbnail":"https://assets.fishersci.com/TFS-Assets/LSG/product-images/QG_AOB_Image_2024.jpg-150.jpg","normalImage":"https://assets.fishersci.com/TFS-Assets/LSG/product-images/QG_AOB_Image_2024.jpg-250.jpg","largeImage":"https://assets.fishersci.com/TFS-Assets/LSG/product-images/QG_AOB_Image_2024.jpg-650.jpg","is360Image":false}],"orderingAttributes":{"Quantity":{"value":"3 Plates","sortValue":0}},"uncondensedPartNumber":"502417809","urls":{"seoUrl":"/shop/products/admetox-80-plex-human-quantigene-plex-panel-3/502417809","promotionUrl":"/ca/en/snippets.promotions.502417809.html","alternatesUrl":"/shop/products/service/alternates/502417809"},"descriptions":{"productLongDescription":"<p>The QuantiGene Plex Human ADMETOX Panel, 80-plex, enables the measurement of gene expression of all relevant ADME (absorption, distribution, metabolism, and excretion) and toxicological biomarkers through the analysis of 80 RNA targets in a single well using Luminex xMAP technology in combination with branched DNA signal amplification. Analyze 80 genetic targets implicated in drug metabolism, including enzymes, transporters, and CYPs, as well as toxicology and apoptosis for efficient profiling of your drug discovery and basic research samples.</p>","teaserText":"The QuantiGene Plex Human ADMETOX Panel, 80-plex, enables the measurement of gene expression of all relevant ADME (absorption, distribution, metabolism, and excretion) and toxicological biomarkers through the analysis of 80 RNA targets in a single well using Luminex xMAP technology in combination with branched DNA signal amplification.","productFeatures":"<p>QuantiGene Plex panels are extensively tested for target combinability, interference, and cross-reactivity to provide the highest level of validation and precision. <b>This kit is not compatible with the MAGPIX instrument</b>.</p><p>This panel is used in combination with the QuantiGene Plex Assay Kit (Cat. No. QP1013), which contains all buffers, plates, and detection reagents necessary to perform the assay in 96-well plates. For detailed information, see <a href=){kind=link}
