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Invitrogen™ ACTR1A Polyclonal Antibody

Description
Antibody detects endogenous levels of total ACTR1A.
This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.
Specifications
Specifications
| Antigen | ACTR1A |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | ACTR1A |
| Gene Accession No. | P61163, P61164, P85515 |
| Gene Alias | actin related protein 1A; actin-related protein 1 alpha; actin-related protein 1 homolog A; actin-RPV; ACTR1A; actr1a {ECO:0000250; alpha-Arp1; alpha-centractin; ARP1; ARP1 actin related protein 1 homolog A; ARP1 actin-related protein 1 homolog A, centractin alpha; ARP1 actin-related protein 1 homolog A, centractin alpha (yeast); ARP1 actin-related protein 1A, centractin alpha; Arp1 centractin alpha; Arp1 contractin alpha; Arp1A; centractin; Centrosome-associated actin homolog; CTRN1; FLJ52695; FLJ52800; FLJ55002; UniProtKB:P61163}; yeast homolog A |
| Gene Symbols | ACTR1A |
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