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Invitrogen™ Human ABL2 (Arg), His Tag Recombinant Protein

Catalog No. PR4795A
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100 μg
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Catalog No. Quantity
PR4795A 100 μg
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Catalog No. PR4795A Supplier Invitrogen™ Supplier No. PR4795A

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Recombinant, Full Length.

ABL2 (Arg) is an Abl-related non-receptor protein tyrosine kinase that links cell surface receptors to cell proliferation and/or cytoskeletal reorganization. Abl2 encodes a member of the Abelson family of nonreceptor tyrosine protein kinase. The protein is highly similar to the ABL1 protein, including the tyrosine kinase, SH2 and SH3 domains, and has a role in cytoskeletal rearrangements by its C-terminal F-actin- and microtubule-binding sequences. Abl2 is expressed in both normal and tumor cells, and is involved in translocation with the ETV6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

Specifications

Accession Number P42684
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50mM tris with 5mM DTT, 0.05% NP-40, 50% glycerol, 200mM NaCl, 2mM EDTA and no preservative; pH 7.5
Gene ID (Entrez) 27
Molecular Weight (g/mol) 130.9 kDa
Name Human ABL2 (Arg), His Tag
pH Range 7.5
Purification Method Purified
Quantity 100 μg
Storage Requirements -80°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias AA536808; Abelson murine leukemia viral (v-abl) oncogene homolog 2; abelson murine leukemia viral oncogene homolog 2; Abelson tyrosine-protein kinase 2; Abelson-related gene protein; ABL proto-oncogene 2, non-receptor tyrosine kinase; Abl1-related gene product; abl2; ABLL; ARG; arg tyrosine kinase; c-abl oncogene 2, non-receptor tyrosine kinase; FLJ22224; FLJ31718; FLJ41441; tyrosine kinase ARG; tyrosine-protein kinase ABL2; Tyrosine-protein kinase ARG; v-abl Abelson murine leukemia viral oncogene 2; v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene); v-abl Abelson murine leukemia viral oncogene homolog 2; v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)
Common Name Abl2
Gene Symbol ABL2
Kinase Family ABL Kinase Family
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-tag
Sequence Full length
Content And Storage Storage Buffer: 50 mM Tris, pH 7.5, 200 mM NaCl, 2 mM EDTA, 0.05% NP-40, 5 mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
Kinase Group Tyrosine Kinases
Shipping Condition Dry Ice
Expression System Insect cells
Protein Form Full Length
Form Liquid
Research Category Drug Development
Purity or Quality Grade 65% by SDS-PAGE
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