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Invitrogen™ ABH1 Recombinant Rabbit Monoclonal Antibody (23GB1385)
Rabbit Recombinant Monoclonal Antibody
Supplier: Invitrogen™ MA554170
Description
ABH1 Recombinant Monoclonal Antibody for Flow, ICC/IF, Western Blot
This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblast lineage differentiation. Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites.Specifications
| ABH1 | |
| Recombinant Monoclonal | |
| 1.5 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| Q13686 | |
| ALKBH1 | |
| A synthesized peptide derived from ALKBH1 (1-85AA). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| 23GB1385 | |
| Unconjugated | |
| ALKBH1 | |
| 2700073G19Rik; Abh; ABH1; alkB; alkB homolog 1, histone H2A dioxygenase; alkB, alkylation repair homolog 1; alkB, alkylation repair homolog 1 (E. coli); ALKBH; Alkbh1; Alkylated DNA repair protein alkB homolog 1; alkylation repair, alkB homolog; alpha-ketoglutarate-dependent dioxygenase ABH1; DNA 6mA demethylase; DNA demethylase ALKBH1; DNA lyase ABH1; DNA N6-methyl adenine demethylase; DNA N6-methyl adenine demethylase ALKBH1; DNA oxidative demethylase ALKBH1; hABH; mRNA N(3)-methylcytidine demethylase; Nucleic acid dioxygenase ALKBH1; tRNA N1-methyl adenine demethylase | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 8846 | |
| -20°C | |
| Liquid |