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Invitrogen™ AASS Polyclonal Antibody
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Catalog No. PIPA554250
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PIPA554250 100 μL
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Catalog No. PIPA554250 Supplier Invitrogen™ Supplier No. PA554250
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Rabbit Polyclonal Antibody

Immunogen sequence: AEWLGLLGDE QVPQAESILD ALSKHLVMKL SYGPEEKDMI VMRDSFGIRH PSGHLEHKTI DLVAYGDING FSAMAKTVGL PTAMAAKMLL DGEIGAKGLM GPFSKEIYGP ILERIKA Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.

AASS is a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in the gene encoding this protein are associated with familial hyperlysinemia.

Specifications

Antigen AASS
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene AASS
Gene Accession No. Q9UDR5
Gene Alias AASS; aass {ECO:0000312; alpha-aminoadipate semialdehyde synthase; alpha-aminoadipic semialdehyde synthase, mitochondrial; aminoadipate-semialdehyde synthase; aminoadipic semialdehyde synthase; EMBL:AAI28772.1}; LKR; LKR/SDH; LKRSDH; LOR; LOR/SDH; Lorsdh; Lysine ketoglutarate reductase; lysine oxoglutarate reductase; lysine-2-oxoglutarate reductase; lysine-ketoglutarate reductase /saccharopine dehydrogenase; saccharopine dehydrogenase; SDH
Gene Symbols AASS
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human AASS. Recombinant protein control fragment (Product #RP-92605).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10157
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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