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  6. Invitrogen™ A2M Monoclonal Antibody (K11079_7B1), Invitrogen™

Invitrogen™ A2M Monoclonal Antibody (K11079_7B1), Invitrogen™

Catalog No. MA556214
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200 μL
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MA556214 200 μL
MA555834 50 μL
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Catalog No. MA556214 Supplier Invitrogen™ Supplier No. MA556214
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Description

Mouse Monoclonal Antibody

Alpha 2-Macroglobulin (a2M), is a approximately 720-kDa homotetrameric glycoprotein composed of four identical approximately 180 kDa subunits. aAlpha 2M shares with other alpha-macroglobulins, like the complement components C3 and C4 and the pregnancy zone protein PZP, an extraordinary binding capacity for a variety of ligands. This allows the alpha-macroglobulins to serve as humoral defense barriers against foreign peptides in the plasma. Alpha 2M interacts and captures virtually any proteinase, often referred to as a panprotease inhibitor. In the brain of Alzheimer's disease (AD) patients, Alpha 2M also has been localized to diffuse amyloid plaques, supporting an important role for alpha 2M in AD etiopathology.

Specifications

Antigen A2M
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone K11079_7B1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Gene A2M
Gene Accession No. P01023
Gene Alias A2M; A2m1; A2maa; A2MAC1; A2MD; A2mp; Alpha 2 M; Alpha-2-M; Alpha-2-M (A2M); alpha-2-macroglobulin; Alpha-2-macroglobulin-P; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; CPAMD5; DKFZp779B086; FWP007; LOC100061656; Mam; S863 7; S863-7
Gene Symbols A2M
Host Species Mouse
Immunogen Alpha 2 macroglobulin purified from human plasma (immunogen is full length).
Purification Method Protein A
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b
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