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9-Fluorenylmethyl chloroformate, 98+%

Catalog No. p-7081631
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AAA1168303 1 g
AAA1168306 5 g
AAA1168314 25 g
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Catalog No. AAA1168303

Supplier: Thermo Scientific Chemicals A1168303

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Store cold | CAS: 28920-43-6 | C15H11ClO2 | 258.701 g/mol

Base sensitive amino protecting group for solid-phase peptide synthesis9-Fluorenylmethyl chloroformate is used in capillary electrophoresis. It acts as a reagent in the precolumn derivatization of amines for HPLC and fluorescent detection. Further, it is used for derivatizing amino acids for HPLC analysis. In addition to this, it is used to prepare N-Fmoc amino acids for solid-phase peptide synthesis and oligonucleotide synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Base sensitive amino protecting group for solid-phase peptide synthesis9-Fluorenylmethyl chloroformate is used in capillary electrophoresis. It acts as a reagent in the precolumn derivatization of amines for HPLC and fluorescent detection. Further, it is used for derivatizing amino acids for HPLC analysis. In addition to this, it is used to prepare N-Fmoc amino acids for solid-phase peptide synthesis and oligonucleotide synthesis.

Solubility
Soluble in dioxane.

Notes
Moisture sensitive. Store in a cool place. Incompatible with alcohols and amines.

Chemical Identifiers

CAS 28920-43-6
Molecular Formula C15H11ClO2
Molecular Weight (g/mol) 258.701
MDL Number MFCD00001138
InChI Key IRXSLJNXXZKURP-UHFFFAOYSA-N
Synonym 9-fluorenylmethyl chloroformate, fmoc-cl, fmoc-chloride, fmoc chloride, 9h-fluoren-9-ylmethyl chloroformate, carbonochloridic acid, 9h-fluoren-9-ylmethyl ester, 9-fluorenylmethoxycarbonyl chloride, 9-fluorenylmethylchloroformate, 9h-fluoren-9-yl methyl carbonochloridate, 9h-fluoren-9-ylmethoxy carbonyl chloride
PubChem CID 34367
IUPAC Name 9H-fluoren-9-ylmethyl carbonochloridate
SMILES C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)Cl

Specifications

Melting Point 60°C to 64°C
Assay Percent Range 98%
Quantity 1 g
UN Number UN2923
Beilstein 2279177
Sensitivity Moisture sensitive
Solubility Information Soluble in dioxane.
Formula Weight 258.7
Percent Purity 98%
Chemical Name or Material 9-Fluorenylmethyl chloroformate
Hazard Category H302+H312+H332-H314-H335
Hazard Statement GHS H Statement
H314-H318-H302-H332
Causes severe skin burns and eye damage.
Causes serious eye damage.
Harmful if swallowed.
Harmful if inhaled.
Precautionary Statement P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c
DOTInformation Hazard Class: 6.1; Packaging Group: II
EINECSNumber 249-313-6
RTECSNumber LQ6250000
TSCA No
storageNote1 Moisture Sensitive
Recommended Storage Keep cold; Store under Nitrogen

RUO – Research Use Only