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6-Aminohexanoic acid, 99%
6-aminohexanoic acid, CAS # 60-32-2, is a synthetic lysine derivative with inhibitory activity against fibrinolysis. It shows hematologic activity. | CAS: 60-32-2 | C6H13NO2 | 131.175 g/mol
Supplier: Thermo Scientific Chemicals A1471936
Description
6-Aminohexanoic acid is used as an intermediate in the polymerization of Nylon-6. It is involved in the extraction of aldehydes from the reaction mixture as well as to improve the solubilization of membrane proteins in electrophoresis. It acts as an inhibitor of fibrinolysis.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- 6-aminohexanoic acid, an epsilon-amino acid, shows an antifibrinolytic and hematologic activity
- This compound competitively inhibits the activation of plasminogen; it consequently reduces the conversion of plasminogen to plasmin (fibrinolysin), an enzyme responsible for the degradation of fibrin clots, fibrinogen, and other plasma proteins, including the procoagulant factors V and VIII
Application
- It has been used as an intermediate in the polymerization of Nylon-6
- It is used for biomolecular applications to extract aldehydes from the reaction mixture and to increase membrane protein solubilization in electrophoresis experiments
- It has been described to inhibit plasminogen binding to activated platelets
- This compound can bind and inactivate carboxypeptidase B
- This compound can also inhibit the activation of the first component of the complement system
Specifications
| 6-Aminohexanoic acid | |
| 210°C to 212°C | |
| C6H13NO2 | |
| MFCD00008238 | |
| 906872 | |
| 6-aminocaproic acid, aminocaproic acid, amicar, epsikapron, capramol, caprocid, epsamon, eaca, acepramin, caprolisin | |
| SLXKOJJOQWFEFD-UHFFFAOYSA-N | |
| 6-aminohexanoic acid | |
| 564 | |
| 131.18 |
| 60-32-2 | |
| ≥99% | |
| H2N(CH2)5CO2H | |
| 500 g | |
| 14,432 | |
| Soluble in water. Slightly soluble in alcohol. Practically insoluble in ether and chloroform. | |
| C(CCC(=O)O)CCN | |
| 131.175 | |
| CHEBI:16586 | |
| 99% |
Chemical Identifiers
| 60-32-2 | |
| 131.175 | |
| SLXKOJJOQWFEFD-UHFFFAOYSA-N | |
| 564 | |
| 6-aminohexanoic acid |
| C6H13NO2 | |
| MFCD00008238 | |
| 6-aminocaproic acid, aminocaproic acid, amicar, epsikapron, capramol, caprocid, epsamon, eaca, acepramin, caprolisin | |
| CHEBI:16586 | |
| C(CCC(=O)O)CCN |
Safety and Handling
GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
H315-H319-H335
EINECSNumber : 200-469-3
RTECSNumber : MO6300000
TSCA : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only