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6(5H)-Phenanthridinone, 96%
CAS: 1015-89-0 | C13H9NO | 195.221 g/mol
$76.26 - $257.74
Chemical Identifiers
| CAS | 1015-89-0 |
|---|---|
| Molecular Formula | C13H9NO |
| Molecular Weight (g/mol) | 195.221 |
| MDL Number | MFCD00004988 |
| InChI Key | RZFVLEJOHSLEFR-UHFFFAOYSA-N |
| Synonym | 6 5h-phenanthridinone, phenanthridin-6 5h-one, 6-phenanthridinol, phenanthridone, 6-5h-phenanthridinone, 6-phenanthridone, 6-phenanthridinone, 6 5h-phenanthridone, phenanthridin-6-ol, phenantridone |
| PubChem CID | 1853 |
| ChEBI | CHEBI:75292 |
| IUPAC Name | 5H-phenanthridin-6-one |
| SMILES | C1=CC=C2C(=C1)C3=CC=CC=C3NC2=O |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AAB2518703
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Thermo Scientific Chemicals
B2518703 |
1 g |
Each for $76.26
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AAB2518706
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Thermo Scientific Chemicals
B2518706 |
5 g |
Each for $257.74
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Description
6(5H)-Phenanthridinone is used as a probe into the role of PARP in cellular response to irradiation. Treatment of cells with 6(5H)-Phenanthridinone and various DNA-damaging agents showed a resistance to apoptosis. It acts as a reactant in the synthesis of 5,6-dihydrophenanthridine sulfonamides, oxidative coupling with diphenylacetylene, direct copper acetate-catalyzed N-cyclopropylation of cyclic amides. It is used as HIV-1 integrase inhibitor.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications6(5H)-Phenanthridinone is used as a probe into the role of PARP in cellular response to irradiation. Treatment of cells with 6(5H)-Phenanthridinone and various DNA-damaging agents showed a resistance to apoptosis. It acts as a reactant in the synthesis of 5,6-dihydrophenanthridine sulfonamides, oxidative coupling with diphenylacetylene, direct copper acetate-catalyzed N-cyclopropylation of cyclic amides. It is used as HIV-1 integrase inhibitor.
Solubility
Soluble in DMSO (5 mg/ml). Insoluble in water.
Notes
Incompatible materials are oxidizing agents. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Chemical Identifiers
| 1015-89-0 | |
| 195.221 | |
| RZFVLEJOHSLEFR-UHFFFAOYSA-N | |
| 1853 | |
| 5H-phenanthridin-6-one |
| C13H9NO | |
| MFCD00004988 | |
| 6 5h-phenanthridinone, phenanthridin-6 5h-one, 6-phenanthridinol, phenanthridone, 6-5h-phenanthridinone, 6-phenanthridone, 6-phenanthridinone, 6 5h-phenanthridone, phenanthridin-6-ol, phenantridone | |
| CHEBI:75292 | |
| C1=CC=C2C(=C1)C3=CC=CC=C3NC2=O |
Specifications
| 1015-89-0 | |
| C13H9NO | |
| 1 g | |
| 6 5h-phenanthridinone, phenanthridin-6 5h-one, 6-phenanthridinol, phenanthridone, 6-5h-phenanthridinone, 6-phenanthridone, 6-phenanthridinone, 6 5h-phenanthridone, phenanthridin-6-ol, phenantridone | |
| RZFVLEJOHSLEFR-UHFFFAOYSA-N | |
| 5H-phenanthridin-6-one | |
| 1853 | |
| 195.22 | |
| 6(5H)-Phenanthridinone |
| 288°C to 294°C | |
| MFCD00004988 | |
| 140641 | |
| Soluble in DMSO (5mg/ml). Insoluble in water. | |
| C1=CC=C2C(=C1)C3=CC=CC=C3NC2=O | |
| 195.221 | |
| CHEBI:75292 | |
| 96% |
Safety and Handling
EINECSNumber : 213-804-3
RTECSNumber : SG0370000
TSCA : No
Recommended Storage : Ambient temperatures
RUO – Research Use Only