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6(5H)-Phenanthridinone, 96%

CAS: 1015-89-0 | C13H9NO | 195.221 g/mol

$76.26 - $257.74

Chemical Identifiers

CAS 1015-89-0
Molecular Formula C13H9NO
Molecular Weight (g/mol) 195.221
MDL Number MFCD00004988
InChI Key RZFVLEJOHSLEFR-UHFFFAOYSA-N
Synonym 6 5h-phenanthridinone, phenanthridin-6 5h-one, 6-phenanthridinol, phenanthridone, 6-5h-phenanthridinone, 6-phenanthridone, 6-phenanthridinone, 6 5h-phenanthridone, phenanthridin-6-ol, phenantridone
PubChem CID 1853
ChEBI CHEBI:75292
IUPAC Name 5H-phenanthridin-6-one
SMILES C1=CC=C2C(=C1)C3=CC=CC=C3NC2=O
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AAB2518703
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Thermo Scientific Chemicals
B2518703
1 g
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AAB2518706
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Thermo Scientific Chemicals
B2518706
5 g
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Description

Description

6(5H)-Phenanthridinone is used as a probe into the role of PARP in cellular response to irradiation. Treatment of cells with 6(5H)-Phenanthridinone and various DNA-damaging agents showed a resistance to apoptosis. It acts as a reactant in the synthesis of 5,6-dihydrophenanthridine sulfonamides, oxidative coupling with diphenylacetylene, direct copper acetate-catalyzed N-cyclopropylation of cyclic amides. It is used as HIV-1 integrase inhibitor.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
6(5H)-Phenanthridinone is used as a probe into the role of PARP in cellular response to irradiation. Treatment of cells with 6(5H)-Phenanthridinone and various DNA-damaging agents showed a resistance to apoptosis. It acts as a reactant in the synthesis of 5,6-dihydrophenanthridine sulfonamides, oxidative coupling with diphenylacetylene, direct copper acetate-catalyzed N-cyclopropylation of cyclic amides. It is used as HIV-1 integrase inhibitor.

Solubility
Soluble in DMSO (5 mg/ml). Insoluble in water.

Notes
Incompatible materials are oxidizing agents. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Specifications

Chemical Identifiers

1015-89-0
195.221
RZFVLEJOHSLEFR-UHFFFAOYSA-N
1853
5H-phenanthridin-6-one
C13H9NO
MFCD00004988
6 5h-phenanthridinone, phenanthridin-6 5h-one, 6-phenanthridinol, phenanthridone, 6-5h-phenanthridinone, 6-phenanthridone, 6-phenanthridinone, 6 5h-phenanthridone, phenanthridin-6-ol, phenantridone
CHEBI:75292
C1=CC=C2C(=C1)C3=CC=CC=C3NC2=O

Specifications

1015-89-0
C13H9NO
1 g
6 5h-phenanthridinone, phenanthridin-6 5h-one, 6-phenanthridinol, phenanthridone, 6-5h-phenanthridinone, 6-phenanthridone, 6-phenanthridinone, 6 5h-phenanthridone, phenanthridin-6-ol, phenantridone
RZFVLEJOHSLEFR-UHFFFAOYSA-N
5H-phenanthridin-6-one
1853
195.22
6(5H)-Phenanthridinone
288°C to 294°C
MFCD00004988
140641
Soluble in DMSO (5mg/ml). Insoluble in water.
C1=CC=C2C(=C1)C3=CC=CC=C3NC2=O
195.221
CHEBI:75292
96%
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Safety and Handling

Safety and Handling

EINECSNumber : 213-804-3

RTECSNumber : SG0370000

TSCA : No

Recommended Storage : Ambient temperatures

SDS
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RUO – Research Use Only