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53BP1 Antibody - BSA Free, R&D Systems™

Catalog No. NB100304
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0.025 mL
0.1 mL
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NB100304 0.1 mL
NB100304SS 0.025 mL
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Catalog No. NB100304 Supplier Bio-Techne Supplier No. NB100304

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Description

A Novus product, part of R&D Systems. Rabbit Polyclonal Antibody

53BP1 Polyclonal specifically detects 53BP1 in Avian, Bat, Bovine, Canine, Drosophila melanogaster, Fish, Goat, Human, Mouse, Naked mole-rat, Pig, Primate, Rabbit, Rat, Reptile samples. It is validated for Chemotaxis, ChIP Assay, FISH, Flow Cytometry, Flow Cytometry (Intracellular Staining), Gene Knock-Out, IF-FISH, IF/ICC, Immunoblot, Immunocytochemistry/Immunofluorescence, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, In Situ Hybridization, In-situ Hybridization, KnockDown, Proximity Ligation Assay, Western Blot.

Specifications

Antigen 53BP1
Applications Chemotaxis, ChIP Assay, FISH, Flow Cytometry, Flow Cytometry (Intracellular Staining), Gene Knock-Out, FISH, Immunoblot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, In Situ Hybridization (ISH), In Situ Hybridization (ISH), KnockDown, Proximity Ligation Assay, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Dilution Western Blot 1:5000-1:25000, Chromatin Immunoprecipitation reported in scientific literature (PMID 24591601), Flow Cytometry 1.5 ug/ml, Immunohistochemistry reported in scientific literature (PMID 24987917), Immunocytochemistry/Immunofluorescence 1:1000-1:5000, Immunoprecipitation reported in scientific literature (PMID 25645366), Immunohistochemistry-Paraffin 1:1000-1:5000. Use reported in scientific literature (PMID 27653664), Immunohistochemistry-Frozen reported by customer review, Immunoblotting reported in multiple pieces of scientific literature, In-situ Hybridization reported in scientific literature (PMID 34988401; 33122290), Flow (Intracellular), Chromatin Immunoprecipitation (ChIP), Knockout Validated reported in scientific literature (PMID 26601238), KnockDown Validated
Formulation PBS with 0.05% Sodium Azide
Gene Accession No. Q12888
Gene Alias 53BP1, p202, p53-binding protein 1, p53bp1, TDRD30, TP53-Binding Protein 1, tumor protein 53-binding protein, 1, tumor protein p53 binding protein 1, tumor protein p53-binding protein, 1, tumor suppressor p53-binding protein 1
Gene Symbols TP53BP1
Host Species Rabbit
Immunogen The epitope recognized by 53BP1 Antibody maps to a region between residues 350 and 400 of human 53BP1 [NP_005648.1].
Molecular Weight of Antigen 214 kDa
Purification Method Affinity Purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Breast Cancer, Cancer, Checkpoint signaling, DNA Double Strand Break Repair, DNA Repair, Tumor Suppressors
Primary or Secondary Primary
Gene ID (Entrez) 7158
Test Specificity Human, mouse, rat and goat. Human has been tested in WB, IHC-P and ICC/IF, mouse and goat have only been tested in ICC/IF. Primate reactivity reported in scientific literature (PMID: 18389475).Fish reactivity reported in scientific literature (PMID: 25516420).
Target Species Avian, Mouse, Bat, Bovine, Canine, Canine, Drosophila melanogaster, Goat, Fish, Goat, Human, Mouse, Naked mole-rat, Pig, Primate, Rabbit, Rat, Reptile
Content And Storage Store at -20 degreesC.
Product Type Antibody
Isotype IgG
Product Line Novus
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For Research Use Only