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Invitrogen™ 4EBP1 Recombinant Rabbit Monoclonal Antibody (23GB1985)

Catalog No. MA553191
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100 μL
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MA553191 20 μL
MA553190 100 μL
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Description

Rabbit Recombinant Monoclonal Antibody

4EBP1 Recombinant Monoclonal Antibody for Flow, ICC/IF, Western Blot

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Specifications

Antigen 4EBP1
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 23GB1985
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene EIF4EBP1
Gene Accession No. Q13541, Q60876, Q62622
Gene Alias 4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1
Gene Symbols EIF4EBP1
Host Species Rabbit
Immunogen A synthesized peptide derived from human eIF4EBP1 (1-46AA).
Purification Method Affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116636, 13685, 1978
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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