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4-Nitrophenyl chloroformate, 97%
CAS: 7693-46-1 | C7H4ClNO4 | 201.562 g/mol
Supplier: Thermo Scientific Chemicals A1874222
Description
4-Nitrophenyl chloroformate is used in the synthesis of poly(oxyethylene) modified dextrans. It is also used to prepare a cleavable, heterobifunctional cross-linker for reversible conjugation of amines to thiol-modified DNA. Further, it is used in the synthesis of mixed, activated carbonates, thiocarbonates and activated urethanes. In addition to this, it is used in the preparation of 4-nitrophenyl diazoacetate with diazomethane.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications4-Nitrophenyl chloroformate is used in the synthesis of poly(oxyethylene) modified dextrans. It is also used to prepare a cleavable, heterobifunctional cross-linker for reversible conjugation of amines to thiol-modified DNA. Further, it is used in the synthesis of mixed, activated carbonates, thiocarbonates and activated urethanes. In addition to this, it is used in the preparation of 4-nitrophenyl diazoacetate with diazomethane.
Solubility
Soluble in acetone, chloroform, acetone, toluene and benzene.
Notes
Moisture sensitive. Store in a cool place. Incompatible with water, acids, alcohols, ammonia, amines and strong bases.
Specifications
| 4-Nitrophenyl chloroformate | |
| 75°C to 82°C | |
| >110°C (230°F) | |
| C7H4ClNO4 | |
| 100 g | |
| 518127 | |
| 4-nitrophenyl chloroformate, carbonochloridic acid, 4-nitrophenyl ester, chloroformic acid 4-nitrophenyl ester, p-nitrophenyl chloroformate, chloroformic acid p-nitrophenyl ester, 4-nitrophenyl carbonochloridate, formic acid, chloro-, p-nitrophenyl ester, 4-nitrophenylchlorocarbonat, 4-nitrophenyl choroformate | |
| NXLNNXIXOYSCMB-UHFFFAOYSA-N | |
| (4-nitrophenyl) carbonochloridate | |
| 82129 | |
| 97% |
| 7693-46-1 | |
| 159°C to 162°C (19 mmHg) | |
| Acrid | |
| MFCD00007321 | |
| UN3261 | |
| Moisture sensitive | |
| Soluble in acetone,chloroform,acetone,toluene and benzene. | |
| C1=CC(=CC=C1[N+](=O)[O-])OC(=O)Cl | |
| 201.562 | |
| 201.57 |
Chemical Identifiers
| 7693-46-1 | |
| 201.562 | |
| NXLNNXIXOYSCMB-UHFFFAOYSA-N | |
| 82129 | |
| C1=CC(=CC=C1[N+](=O)[O-])OC(=O)Cl |
| C7H4ClNO4 | |
| MFCD00007321 | |
| 4-nitrophenyl chloroformate, carbonochloridic acid, 4-nitrophenyl ester, chloroformic acid 4-nitrophenyl ester, p-nitrophenyl chloroformate, chloroformic acid p-nitrophenyl ester, 4-nitrophenyl carbonochloridate, formic acid, chloro-, p-nitrophenyl ester, 4-nitrophenylchlorocarbonat, 4-nitrophenyl choroformate | |
| (4-nitrophenyl) carbonochloridate |
Safety and Handling
GHS H Statement
H301-H314-H318-H332
Toxic if swallowed.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Harmful if inhaled.
P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c
H301+H311+H331-H314-H335
DOTInformation : Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S.
EINECSNumber : 231-706-9
TSCA : Yes
Recommended Storage : Keep cold
RUO – Research Use Only