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  7. 4',7-Dihydroxyisoflavone, 97%

4',7-Dihydroxyisoflavone, 97%

Catalog No. AAB2287703
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Quantity:
1 g
25 g
5 g
Catalog No. Quantity
AAB2287703 1 g
AAB2287706 5 g
AAB2287714 25 g
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Catalog No. AAB2287703

Supplier: Thermo Scientific Chemicals B2287703

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Description

CAS: 486-66-8 | C15H10O4 | 254.241 g/mol

4',7-Dihydroxyisoflavone is a phytoestrogen that is suggested to play a role in preventing hormone-induced cancers. It protects against oxidative damage in liver cells induced by 7,12-dimethylbenz[a]anthracene (DMBA). Catalase and superoxide dismutase activity, down-regulated by DMBA, was restored by daidzein.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4′,7-Dihydroxyisoflavone is a phytoestrogen that is suggested to play a role in preventing hormone-induced cancers. It protects against oxidative damage in liver cells induced by 7,12-dimethylbenz[a]anthracene (DMBA). Catalase and superoxide dismutase activity, down-regulated by DMBA, was restored by daidzein.

Solubility
Insoluble in water. Soluble in DMSO (25 mg/ml), ethanol (2 mg/ml), DMF (10 mg/ml), and 1:10 DMSO:PBS (pH 7.2) (0.15 mg/ml).

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents and heat.

Chemical Identifiers

CAS 486-66-8
Molecular Formula C15H10O4
Molecular Weight (g/mol) 254.241
MDL Number MFCD00016954
InChI Key ZQSIJRDFPHDXIC-UHFFFAOYSA-N
Synonym daidzein, 4',7-dihydroxyisoflavone, daidzeol, 7,4'-dihydroxyisoflavone, 7-hydroxy-3-4-hydroxyphenyl-4h-chromen-4-one, diadzein, 7-hydroxy-3-4-hydroxyphenyl-4h-1-benzopyran-4-one, 4h-1-benzopyran-4-one, 7-hydroxy-3-4-hydroxyphenyl, 7-hydroxy-3-4-hydroxyphenyl chromen-4-one, 7-hydroxy-3-4-hydroxyphenyl-4-benzopyrone
PubChem CID 5281708
ChEBI CHEBI:28197
IUPAC Name 7-hydroxy-3-(4-hydroxyphenyl)chromen-4-one
SMILES C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3)O)O

Specifications

Melting Point 328°C to 332°C (decomposition)
Quantity 1 g
Beilstein 231523
Merck Index 14,2801
Solubility Information Insoluble in water. Soluble in DMSO (25mg/ml),ethanol (2mg/ml),DMF (10mg/ml),and 1:10 DMSO:PBS (pH 7.2) (0.15mg/ml).
Formula Weight 254.24
Percent Purity 97%
Chemical Name or Material 4',7-Dihydroxyisoflavone

Safety and Handling

Hazard Category H315-H319
Hazard Statement GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P264b-P280-P302+P352-P305+P351+P338-P332+P313-P362
EINECSNumber 207-635-4
RTECSNumber DJ3100040
TSCA No

RUO – Research Use Only