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  7. 3-(Trimethylsilyl)propargyl alcohol, 98%

3-(Trimethylsilyl)propargyl alcohol, 98%

Catalog No. AAL0964903
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Quantity:
1 g
25 g
5 g
Catalog No. Quantity
AAL0964903 1 g
AAL0964906 5 g
AAL0964914 25 g
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Catalog No. AAL0964903

Supplier: Thermo Scientific Chemicals L0964903

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Description

CAS: 5272-36-6 | C6H12OSi | 128.25 g/mol

3-(Trimethylsilyl)propargyl alcohol is used as a reagent to synthesize Isbogrel, a Thromboxane A 2 (TXA 2) synthase inhibitor and also a TXA 2 receptor antagonist that has potential to treat asthma.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3-(Trimethylsilyl)propargyl alcohol is used as a reagent to synthesize Isbogrel, a Thromboxane A 2 (TXA 2) synthase inhibitor and also a TXA 2 receptor antagonist that has potential to treat asthma.

Solubility
Not miscible with water.

Notes
Moisture Sensitive. Store away from moisture and oxidizing agents. Protect from heat. Store under dry inert gas. Protect from humidity and water. Incompatible with oxidizing agents, heat and moisture.

Chemical Identifiers

CAS 5272-36-6
Molecular Formula C6H12OSi
Molecular Weight (g/mol) 128.25
MDL Number MFCD00002913
InChI Key ZVGCJDPEKKEYES-UHFFFAOYSA-N
Synonym 3-trimethylsilyl-2-propyn-1-ol, 3-trimethylsilyl propargyl alcohol, 2-propyn-1-ol, 3-trimethylsilyl, 3-trimethylsilyl prop-2-yn-1-ol, 1-trimethylsilylpropargyl alcohol, acmc-209l1b, 3-trimethylsilylpropargyl alcohol, 3-trimethylsilanyl-prop-2-yn-1-ol, 3-trimethylsilyl-2-propyn-1-ol #
PubChem CID 78930
IUPAC Name 3-trimethylsilylprop-2-yn-1-ol
SMILES C[Si](C)(C)C#CCO

Specifications

Boiling Point 170°C to 172°C
Quantity 1 g
Linear Formula (CH3)3SiC≡CCH2OH
UN Number UN2810
Beilstein 1902505
Flash Point 66°C (150°F)
Solubility Information Not miscible with water.
Formula Weight 128.25
Percent Purity ≥98%
Refractive Index 1.451
Sensitivity Moisture sensitive
Density 0.865
Chemical Name or Material 3-(Trimethylsilyl)propargyl alcohol
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Safety and Handling

Hazard Category H227-H315-H319-H335
Hazard Statement GHS H Statement
H301-H227-H315-H319-H335
Toxic if swallowed.
Combustible liquid.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P210-P235-P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P370+P378q-P501c
DOTInformation Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC, LIQUIDS, ORGANIC, N.O.S.
EINECSNumber 226-094-5
TSCA Yes
Recommended Storage Keep cold

RUO – Research Use Only