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  7. 3-Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt, 97+%

3-Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt, 97+%

Catalog No. AAH54807MB
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Catalog No. AAH54807MB Supplier Thermo Scientific Chemicals Supplier No. H54807MB
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Description

CAS: 92921-24-9 | C16H17N2NaO9S | 436.367 g/mol

3-Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt is a cross-linking reagent incorporating an extended spacer with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3-Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt is a cross-linking reagent incorporating an extended spacer with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.

Solubility
Soluble in water (2.5 mg/ml) and dimethyl formamide.

Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.

Chemical Identifiers

CAS 92921-24-9
Molecular Formula C16H17N2NaO9S
Molecular Weight (g/mol) 436.367
MDL Number MFCD00054978
InChI Key VUFNRPJNRFOTGK-UHFFFAOYSA-M
Synonym sulfo-smcc, sodium 1-4-2,5-dioxo-2,5-dihydro-1h-pyrrol-1-yl methyl cyclohexanecarbonyl oxy-2,5-dioxopyrrolidine-3-sulfonate, sulfo-smcc sodium, 4-maleimidomethyl cyclohexane-1-carboxylic acid 3-sulfo-n-hydroxysuccinimide ester sodium salt, 3-sulfo-n-succinimidyl 4-n-maleimidomethyl cyclohexane-1-carboxylate sodium salt, sulfo-trans-smcc, sulfo-smcc crosslinker, sulfo-n-succinimidyl 4-maleimidomethyl cyclohexane-1-carboxylate sodium salt, sulfo-smcc sodium salt, bicl207
PubChem CID 4618794
IUPAC Name sodium;1-[4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexanecarbonyl]oxy-2,5-dioxopyrrolidine-3-sulfonate
SMILES C1CC(CCC1CN2C(=O)C=CC2=O)C(=O)ON3C(=O)CC(C3=O)S(=O)(=O)[O-].[Na+]

Specifications

Quantity 25 mg
Solubility Information Soluble in water (2.5mg/ml) and dimethyl formamide.
Formula Weight 436.37
Percent Purity ≥98%
Chemical Name or Material 3-Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt

Safety and Handling

Hazard Category H315-H319-H335
Hazard Statement GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA No
Recommended Storage Keep cold

RUO – Research Use Only